The Ultimate Guide To megatomi.com

Our new Very clear+ tissue clearing strategy is the only real process that delipidates samples with no modify in morphology and with nominal influence on structural integrity.

Megatome is usually a vibrating microtome designed to segment a broad array of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With substantial blade vibrating frequency and minimized blade deflection, Megatome permits superior-throughput tissue sectioning with uniform area profile, as well as minimum tissue harm and data reduction.

Antibodies could get weeks to diffuse by means of just a few millimeters of tissue, using a steep labeling gradient from surface area to core.

Megatome is made for accuracy: the blade vibrates at an increased frequency and larger amplitude assortment than other microtomes, and includes a special deflection Manage mechanism.

SE makes use of a rotational electric field to disperse really electromobile molecules (which include antibodies or surfactant micelles) in the course of a porous sample with no detrimental electrically charged structures throughout the tissue. This allows two-4 day clearing of intact organs,

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Megatome is actually a novel microtome which allows for prime-precision sectioning of a wide range of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with minimum tissue damage and data loss.

It’s time to up grade your microtome to Megatome. With correct superior-frequency slicing for an unmatched variety of sample sizes and kinds – from organoids and tumors megatomi.com to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for numerous apps.

Absolutely delipidate entire mouse brains or comparably sized samples in only one day with SmartBatch+, or in a single week with our passive clearing kit.

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Our novel Protect tissue preservation system forms intramolecular bonds utilizing polyfunctional, versatile epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.